Hi!
EDFX use Reshade 1.1,
Skypat say in his last release note "when a reShade framework 2.x version is detected, added user warning message, EDFX won't use it." so the message about Reshade 2.x seems to be just a warning,
I suppose you have 1.1 & 2.x installed so just ignore the message if everything work well.